Difference between revisions of "Altretamine (Hexalen)"

From HemOnc.org - A Hematology Oncology Wiki
Jump to navigation Jump to search
m (Text replacement - "[[Category:Drugs FDA" to "[[Category:FDA")
Line 17: Line 17:
  
 
==Also known as==
 
==Also known as==
*'''Generic names:''' Hexamethylmelamine, HMM
+
*'''Generic names:''' hexamethylmelamine, HMM
*'''Brand name:''' Altretamine
+
*'''Brand name:''' Hexalen, Hexastat
  
 
==References==
 
==References==

Revision as of 14:14, 24 November 2018

General information

Class/mechanism: Alkylating-like, exact mechanism unknown—can form covalent adducts with tissue macromolecules including DNA.[1][2]
Route: PO
Extravasation: n/a

For conciseness and simplicity, HemOnc.org currently will focus on treatment regimens and not list information such as: renal/hepatic dose adjustments, metabolism (including CYP450), excretion, monitoring parameters (although this will be considered for checklists), or manufacturer. Instead, for the most current information, please refer to your preferred pharmacopeias such as Micromedex, Lexicomp, Medscape,UpToDate (courtesy of Lexicomp), or the prescribing information.[1]

Diseases for which it is used

Patient drug information

History of changes in FDA indication

  • 12/26/1990: Initial FDA approval

Also known as

  • Generic names: hexamethylmelamine, HMM
  • Brand name: Hexalen, Hexastat

References